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Ledip AS vir-ace to ne

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (12) ADC Linker (3) Adrenergic Receptor (9) Akt (1) Aldose Reductase (1) Amino Acid Derivatives (1) Androgen Receptor (2) Angiotensin Receptor (1) Antibiotic (4) Apoptosis (4) ATF6 (1) Aurora Kinase (1) Autophagy (5) Bacterial (6) Bcr-Abl (1) Biochemical Assay Reagents (9) Caspase (1) CDK (2) Cholinesterase (ChE) (3) COX (1) CRM1 (1) Cytochrome P450 (4) DNA Methyltransferase (1) DNA Stain (1) DNA/RNA Synthesis (1) Dopamine Transporter (4) Drug Metabolite (2) Drug-Linker Conjugates for ADC (1) E1/E2/E3 Enzyme (1) Elastase (4) Endogenous Metabolite (4) Epigenetic Reader Domain (2) Estrogen Receptor/ERR (1) Filovirus (2) FLT3 (1) Fluorescent Dye (3) Free Fatty Acid Receptor (1) Fungal (1) GHSR (1) GPR119 (1) GPR4 (1) Histamine Receptor (1) Histone Acetyltransferase (1) Histone Demethylase (1) Histone Methyltransferase (4) HIV (1) Isotope-Labeled Compounds (7) JNK (2) Leukotriene Receptor (1) Liposome (1) Lipoxygenase (1) LPL Receptor (1) MDM-2/p53 (2) MEK (1) MicroRNA (8) Microtubule/Tubulin (1) Monoamine Transporter (1) NF-κB (1) Nucleoside Antimetabolite/Analog (1) p38 MAPK (1) Parasite (2) Phosphatase (2) PI3K (4) PKC (1) Potassium Channel (7) Prostaglandin Receptor (1) RAR/RXR (1) Ras (1) ROCK (1) Ser/Thr Protease (2) Serotonin Transporter (18) Sigma Receptor (1) Small Interfering RNA (siRNA) (5) Sodium Channel (2) STAT (6) Topoisomerase (1) Transthyretin (TTR) (1) TRP Channel (2) Vasopressin Receptor (1)
By Research Areas:	Cancer (60) Cardiovascular Disease (8) Endocrinology (6) Infection (9) Inflammation/Immunology (27) Metabolic Disease (13) Neurological Disease (41)
Click Chemistry:	Labeling and Fluorescence Imaging (1) Alkynes (1)

177

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Click Chemistry

Targets Recommended: Angiotensin-converting Enzyme (ACE)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101484A

NE-100 hydrochloride	Sigma Receptor	Neurological Disease
NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC₅₀ of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo[1]. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death[2].

HY-78932A

Dap-NE hydrochloride	ADC Linker	Cancer
Dap-NE hydrochloride is a dipeptide hydrochloride and a cleavable ADC Linker.Dap-NE hydrochloride can be used to connect Antibody and toxin molecules (Cytotoxin) to synthesize Antibody-Drug Conjugates (ADCs) .

HY-18600A

Azimilide dihydrochloride 2 Publications Verification ne-10064 dihydrochloride	Potassium Channel	Cardiovascular Disease
Azimilide (NE-10064) dihydrochloride is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-16011

NE 10790 1 Publications Verification 3-PEHPC	Others	Others
NE 10790, a poor farnesyl pyrophosphate synthase inhibitor, is a phosphonocarboxylate analogue of the potent bisphosphonate risedronate and is a weak antiresorptive agent.

HY-126825

NE21650	Others	Metabolic Disease
NE21650 potently inhibits farnesyl diphosphate (FPP) synthase. NE21650 is a weak inhibitor of isopentenyl diphosphate (IPP) isomerase. NE21650 is a potent inhibitor of protein prenylation in osteoclasts and macrophages and bone resorption in vitro .

HY-78931G

Boc-Dap-NE	ADC Linker	Cancer
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-106823

Tebufelone ne-11740	COX Lipoxygenase	Neurological Disease Inflammation/Immunology
Tebufelone (NE-11740), a nonsteroidal anti-inflammatory drug (NSAID), is a selective dual COX-2/5-lipoxygenase inhibitor. Tebufelone displays potent anti-inflammatory, analgesic and anti-pyretic properties .

HY-101323

Olvanil

ne-19550; N-Vanillyloleamide

Olvanil (NE-19550) is an analgesic and an agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with an EC₅₀ of 0.7 nM .

Olvanil ne-19550; N-Vanillyloleamide
Olvanil (NE-19550) is an analgesic and an agonist of transient receptor potential vanilloid type 1 (TRPV1) channels with an EC₅₀ of 0.7 nM .

HY-101784

NE 52-QQ57 2 Publications Verification	GPR4	Inflammation/Immunology
NE 52-QQ57 is a selective, and orally available GPR4 antagonist with an IC₅₀ of 70 nM. NE 52-QQ57 has anti-inflammatory activity .

HY-78932

Dap-NE

Others Cancer

Dap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162) .

Dap-NE	Others	Cancer
Dap-NE is an intermediate reagent in the synthesis of the ADC toxin Monomethyl auristatin E (HY-15162) .

HY-78931C

(S,S,R,S,R)-Boc-Dap-NE	Others	Cancer
(S,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-78931E

(R,S,R,S,R)-Boc-Dap-NE	Others	Cancer
(R,S,R,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-78931F

(R,S,S,S,R)-Boc-Dap-NE	Others	Cancer
(R,S,S,S,R)-Boc-Dap-NE is an isomer of the dipeptide Boc-Dap-NE (HY-78931). Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-78931A

(R,S,S,R,S)-Boc-Dap-NE	Others	Cancer
(R,S,S,R,S)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-78931B

(S,S,S,S,R)-Boc-Dap-NE	Others	Cancer
(S,S,S,S,R)-Boc-Dap-NE is the inactive isomer of Boc-Dap-NE (HY-78931), and can be used as an experimental control. Boc-Dap-NE, is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-18600

Azimilide ne-10064	Potassium Channel	Cardiovascular Disease
Azimilide(NE-10064) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-78931

Boc-Dap-NE	ADC Linker	Cancer
Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-18600AS

Azimilide-d8 dihydrochloride ne-10064-dd₈ dihydrochloride	Isotope-Labeled Compounds Potassium Channel	Cardiovascular Disease
Azimilide-d₈ (dihydrochloride) is the deuterium labeled Azimilide dihydrochloride. Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-78932C

(2S,3R)-Dap-NE hydrochloride	Others	Cancer
(2S,3R)-Dap-NE hydrochloride is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .

HY-78932D

(2R,3R)-Dap-NE hydrochloride	Others	Cancer
(2R,3R)-Dap-NE hydrochloride is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity .

HY-108039

Bezisterim HE 3286; ne-3107	NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology
Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrier in mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis . Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-B0196

Venlafaxine 1 Publications Verification Wy 45030	Serotonin Transporter	Neurological Disease Cancer
Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant .

HY-B0196A

Venlafaxine hydrochloride 1 Publications Verification Wy 45030 hydrochloride	Serotonin Transporter	Neurological Disease Cancer
Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant .

HY-P3648

Ala-Ala-Pro-Val-chloromethylketone AAPV-CMK	Elastase	Inflammation/Immunology
Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases .

HY-107562

JNJ 10181457 dihydrochloride	Histamine Receptor	Neurological Disease
JNJ-10181457 is a neutral, potent, brain-penetrant and selective non-imidazole H₃ antagonist which increases NE and ACh concentrations in rat frontal cortex. JNJ-10181457 can be used for neurological research .

HY-118064

(R)-Thionisoxetine LY-368975	Others	Neurological Disease
(R)-Thionisoxetine is a potent and selective inhibitor of central and peripheral norepinephrine (NE) uptake. (R)-thionisoxetine prevented hypothalamic NE depletion by 6-hydroxydopamine with an ED₅₀ of 0.21 mg/kg. (R)-Thionisoxetine can be used for the research of a variety of diseases including depression and urinary incontinence .

HY-N6847

5,6,7,40-Tetrahydroxyisoflavone-6,7-di-o-b-D-glucopyranoside	Others	Others
5,6,7,40-Tetrahydroxyisoflavone-6,7-di-o-b-D-glucopyranoside is an isoflavonoid glycoside isolated from Pueraria lobata .

HY-D0917

TO-PRO 1	DNA Stain	Cancer
TO-PRO 1 is a DNA binding fluorochrome, that atached to the surface of the Feraheme (FH) nanoparticle (NP), to obtain a fluorochrome-functionalized NP. TO-PRO 1 binds DNA through intercalation, and acts as a vital fluorochrome for necrotic cells .

HY-101810

Tazanolast

to 188; Tazalest; Tazanol
Others Inflammation/Immunology

Tazanolast is a selective mast-cell-stabilizing agent, on ozone-induced airway hyperresponsiveness in guinea pigs.
HY-144246S

Zofenoprilat-NES-d5

Isotope-Labeled Compounds Others

Zofenoprilat-NES-d₅ is the deuterium labeled Zofenoprilat-NES[1].

Tazanolast to 188; Tazalest; Tazanol	Others	Inflammation/Immunology
Tazanolast is a selective mast-cell-stabilizing agent, on ozone-induced airway hyperresponsiveness in guinea pigs.

Zofenoprilat-NES-d5	Isotope-Labeled Compounds	Others
Zofenoprilat-NES-d₅ is the deuterium labeled Zofenoprilat-NES[1].

HY-N1745

2'-O-Methylisoliquiritigenin
2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway .

HY-W008794S

Normetanephrine-d3 hydrochloride (±)-Normetanephrine-d₃ (hydrochloride); DL-Normetanephrine-d₃ (hydrochloride); (Rac)-Normetanephrine-d₃ (hydrochloride)	Endogenous Metabolite	Metabolic Disease
Normetanephrine-d₃ (hydrochloride) is the deuterium labeled Normetanephrine hydrochloride. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE)[1].

HY-117070

TO-PRO-3 iodide

Fluorescent Dye Others

TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer.

TO-PRO-3 iodide	Fluorescent Dye	Others
TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer.

HY-14761

Bentamapimod 5+ Cited Publications AS 602801	JNK	Cancer
Bentamapimod (AS 602801) is an ATP-competitive JNK inhibitor with IC₅₀ of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.

HY-RS09211

NES Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
NES Human Pre-designed siRNA Set A contains three designed siRNAs for NES gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

NES Human Pre-designed siRNA Set A NES Human Pre-designed siRNA Set A

HY-16736A

Centanafadine hydrochloride EB-1020 hydrochloride	Adrenergic Receptor Dopamine Transporter Serotonin Transporter	Neurological Disease Endocrinology
Centanafadine (hydrochloride) is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC₅₀s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively.

HY-16736

Centanafadine EB-1020	Adrenergic Receptor Dopamine Transporter Serotonin Transporter	Neurological Disease Endocrinology
Centanafadine is dual norepinephrine (NE)/dopamine (DA) transporter inhibitor, also inhibits serotonin transporter, with IC₅₀s of 6 nM, 38 nM and 83 nM for human NE, DA and serotonin transporter , respectively.

HY-147081

AS 1411 AGRO-100	Others	Cancer
AS1411 is a nucleic acid aptamer that targets nucleolin. AS1411 can deliver nanoparticles, oligonucleotides, and small molecules to cancer cells, exerting antitumor effects .

HY-P0041A

F992 TFA

Vasopressin Receptor Neurological Disease

F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

F992 TFA	Vasopressin Receptor	Neurological Disease
F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-W008794

Normetanephrine hydrochloride (±)-Normetanephrine hydrochloride; DL-Normetanephrine hydrochloride; (Rac)-Normetanephrine hydrochloride	Endogenous Metabolite	Metabolic Disease
Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE) .

HY-10109

AS-605240

5 Publications Verification

PI3K Autophagy Cancer

AS-605240 is a specific and orally active inhibitor of the PI3Kγ, with an IC₅₀ of 8 nM, and a K_i of 7.8 nM.
HY-13532

AS-252424

3 Publications Verification

PI3K Cancer

AS-252424 is a potent and selective PI3Kγ inhibitor with an IC₅₀ of 30±10 nM.

AS-605240 5 Publications Verification	PI3K Autophagy	Cancer
AS-605240 is a specific and orally active inhibitor of the PI3Kγ, with an IC₅₀ of 8 nM, and a K_i of 7.8 nM.

AS-252424 3 Publications Verification	PI3K	Cancer
AS-252424 is a potent and selective PI3Kγ inhibitor with an IC₅₀ of 30±10 nM.

HY-11010

AS601245 5 Publications Verification	JNK	Neurological Disease Inflammation/Immunology Cancer
AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC₅₀s of 150, 220, and 70 nM for three JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively. AS601245 exhibits 10- to 20-fold selectivity over c-src, CDK2, and c-Raf and more than 50- to 100-fold selectivity over a range of Ser/Thr- and Tyr-protein kinases. Neuroprotective properties .

HY-100614

AS1517499

20+ Cited Publications

STAT Inflammation/Immunology Cancer

AS1517499 is a potent and brain-permeable STAT6 phosphorylation inhibitor with an IC₅₀ of 21 nM.

AS1517499 20+ Cited Publications	STAT	Inflammation/Immunology Cancer
AS1517499 is a potent and brain-permeable STAT6 phosphorylation inhibitor with an IC₅₀ of 21 nM.

HY-100596

AS1842856 Maximum Cited Publications 46 Publications Verification	Autophagy	Metabolic Disease
AS1842856, a specific Foxo1 inhibitor (IC₅₀=30 nM), potently suppresses autophagy . AS1842856 only reduces the activity of FoxO1 by binding with it, without affecting its transcription and protein expression .

HY-101946

AS-35	Leukotriene Receptor	Inflammation/Immunology
AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum with IC₅₀ values of 8 nM, 4 nM and 3 nM, respectively, and has antiallergic activities.

HY-12663

AS2521780

PKC Inflammation/Immunology

AS2521780 is a novel PKCθ selective inhibitor with an IC₅₀ of 0.48 nM.

HY-114379

AS2717638 1 Publications Verification	LPL Receptor	Inflammation/Immunology
AS2717638 is an oral active and selective lysophosphatidic acid receptor 5 (LPA5) antagonist, with an IC₅₀ of 38 nM for hLPA5. AS2717638 also significantly improves PGE₂-, PGF_2α-, and AMPA-induced allodynia .

HY-18686

AS1949490
AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC₅₀ values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes .

HY-126675A

AS2863619	CDK STAT	Inflammation/Immunology
AS2863619 enables conversion of antigen-specific effector/memory T cells into Foxp3 ⁺ regulatory T (T_reg) cells for the treatment of various immunological diseases. AS2863619 is a potent, orally active cyclin-dependent kinase 8 (CDK8) and CDK19 inhibitor with IC₅₀s of 0.61 nM and 4.28 nM, respectively. STAT5 activation enhanced by AS2863619 inhibition of CDK8/19, which consequently activates the Foxp3 gene .

Cat. No.	Product Name	Type

HY-117070

TO-PRO-3 iodide

Fluorescent Dyes/Probes

TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer.

HY-78932G

Dap-NE hydrochloride (GMP)	Fluorescent Dye
Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs) .

HY-78931G

Boc-Dap-NE (GMP)	Fluorescent Dye
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-D0917

TO-PRO 1	DNA Stain
TO-PRO 1 is a DNA binding fluorochrome, that atached to the surface of the Feraheme (FH) nanoparticle (NP), to obtain a fluorochrome-functionalized NP. TO-PRO 1 binds DNA through intercalation, and acts as a vital fluorochrome for necrotic cells .

HY-113823

Naphthol AS-G

Fluorescent Dyes/Probes

Naphthol AS-G is an active compound. Naphthol ASG can be used for a series of synthetic organic pigments (SOP’s) research .
HY-D0164

Naphthol AS-BI

Dyes

Naphthol AS-BI is a substrate of β-glucuronidase and produces a bright red effect after staining biological tissues.

HY-D1520

Naphthol AS-GR phosphate disodium	Fluorescent Dyes/Probes
Naphthol AS-GR phosphate disodium is substrates for acid and alkaline phosphatases. Naphthol AS-GR phosphate disodium has an intense green fluorescence used in histochemical studies .

HY-D1190

DC271	Fluorescent Dyes/Probes
DC271 is a RAR agonist that can be considered a retinoid, eliciting cellular responses consistent with the endogenous retinoid ATRA and the synthetic retinoid EC23. DC271 binds to retinoid protein machinery, including CRABPII, to translocate the endogenous retinoid ATRA into the nucleus .

Cat. No.	Product Name	Type

HY-78932G

Dap-NE hydrochloride (GMP)	Biochemical Assay Reagents
Dap-NE hydrochloride (GMP) is Dap-NE hydrochloride (HY-78932A) produced by using GMP guidelines. Dap-NE hydrochloride is an intermediate used in the synthesis of antibody-drug conjugates (ADCs) .

HY-78931G

Boc-Dap-NE (GMP)	Biochemical Assay Reagents
Boc-Dap-NE (GMP) is Boc-Dap-NE (HY-78931) produced by using GMP guidelines. Boc-Dap-NE is an intermediate in the synthesis of Monomethyl auristatin E (HY-15162), which is an inhibitor of tubulin polymerization. Monomethyl auristatin E can be used to synthesize Antibody-Drug Conjugates (ADCs) as ADC Cytotoxin.

HY-W145571

3A-Amino-3A-deoxy-(2AS,3AS)-γ-cyclodextrin 3A-Amino-3A-deoxy-(2AS,3AS)-gamma-cyclodextrin	Biochemical Assay Reagents
3A-Amino-3A-deoxy-(2AS,3AS)-γ-cyclodextrin Hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145532

3A-Amino-3A-deoxy-(2AS,3AS)-α-cyclodextrin 3A-Amino-3A-deoxy-(2AS,3AS)-alpha-cyclodextrin	Biochemical Assay Reagents
3A-Amino-3A-deoxy-(2AS,3AS)-α-cyclodextrin Hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W145671

3A-Amino-3A-deoxy-(2AS,3AS)-β-cyclodextrin 3A-Amino-3A-deoxy-(2AS,3AS)-beta-cyclodextrin	Biochemical Assay Reagents
3A-Amino-3A-deoxy-(2AS,3AS)-β-cyclodextrin Hydrate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-130767

Naphthol AS-TR phosphate

Biochemical Assay Reagents

Naphthol AS-TR Phosphate is a water-soluble dye commonly used as an enzyme substrate in various biochemical assays to detect alkaline phosphatase activity. Naphthol AS-TR Phosphate has unique chemical properties that allow it to be hydrolyzed by alkaline phosphatase to form a colored product that can be detected spectrophotometrically. This makes it a useful tool for monitoring enzyme activity in biological samples such as serum or urine.

HY-137833

Naphthol AS-BI glucuronide Naphthol AS-BI β-D-glucuronide	Biochemical Assay Reagents
Naphthol AS-BI β-D-Glucuronide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0276

m-Cresol purple sodium Metacresol purple sodium	Biochemical Assay Reagents
m-Cresol purple sodium (Metacresol purple sodium) is a pH indicator. m-Cresol purple sodium solution from yellow to blue in the pH range from 7.5 to 9.0 .

HY-137854

Naphthol AS-BI N-acetyl-β-D-glucosaminide	Enzyme Substrates
Naphthol AS-BI N-acetyl-β-D-glucosaminide acts as a substrate and reacts directly with N-acetyl-β-glucosaminidase enzyme. Naphthol AS-BI N-acetyl-β-D-glucosaminide can detect and localize the active region of N-acetyl-β-glucosaminidase enzyme visually .

HY-150229

306-N16B	Drug Delivery
306-N16B is a lipid and allows systemic codelivery of Cas9 mRNA and sgRNA. 306-N16B can transport mRNA to the pulmonaryendothelial cell. 306-N16B can be used for research of genome editing-based therapies .

Cat. No.	Product Name	Target	Research Area

HY-P0041A

F992 TFA

Vasopressin Receptor Neurological Disease

F992 TFA is an antidiuretic peptide and vasopressin (antidiuretic hormone) analogue .

HY-P3432

DfTat	Peptides	Others
DfTat is a dimer of the prototypical cell-penetrating peptide TAT. DfTat can deliver small molecules, peptides and proteins into live cells with a particularly high efficiency. DfTat labeled with the rhodamine can be used as a tracer for easy detection .

HY-P3648

Ala-Ala-Pro-Val-chloromethylketone AAPV-CMK	Elastase	Inflammation/Immunology
Ala-Ala-Pro-Val-chloromethylketone is an irreversible human neutrophil elastase (NE) inhibitor for use in the study of chronic inflammatory airway diseases .

HY-P5740

Cacaoidin	Bacterial	Infection
Cacaoidin is a glycosylated lantibiotic isolated from a Streptomyces cacaoi strain. Cacaoidin has potent antibacterial activity against Gram-positive pathogens including Clostridium difficile .

HY-P5970

DABCYL-TNF-α-EDANS (-4 to +6) (human)

Tace Substrate
Peptides Cancer

DABCYL-TNF-α-EDANS (-4 to +6) (human) is a FRET peptide substrate of tumor necrosis factor convertase (TACE) .

HY-P3064

Scyllatoxin Leiurotoxin I	Potassium Channel	Neurological Disease
Scyllatoxin (Leiurotoxin I) is a peptide toxin, it can be isolated from the venom of the scorpion (Leiurus quinquestriatus hebraeus). Scyllatoxin is a blocker of small-conductance K_Ca (SK) channel. Scyllatoxin enhances both norepinephrine (NE) and epinephrine (Epi) release in vivo .

HY-P3761

Ac-Tyr-Val-Lys-Asp-aldehyde	Caspase	Others
Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia .

HY-W072147

Fmoc-Ser-OMe Fmoc-L-Ser-OMe	Amino Acid Derivatives	Others
Fmoc-Ser-OMe (Fmoc-L-Ser-OMe) is a hydroxylated L-amino acid protected with a 9-fluorenylmethyloxycarbonyl (Fmoc) group. Fmoc-Ser-OMe involves in chlorophyll–amino acid conjugates synthesis, and acts as a chromo/fluorophores modified protein and emits visible to near-infrared lights efficiently. Fmoc-Ser-OMe glycosylates and produces small mucin-related Olinked glycopeptides, as an alcohol acceptor .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W008794

Normetanephrine hydrochloride (±)-Normetanephrine hydrochloride; DL-Normetanephrine hydrochloride; (Rac)-Normetanephrine hydrochloride	Classification of Application Fields Source classification Phenols Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE) .

HY-N7404

Nε,Nε,Nε-Trimethyllysine chloride ne-(Trimethyl)-L-lysine chloride; H-Lys(Me)3-OH chloride	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA) .

HY-N6847

5,6,7,40-Tetrahydroxyisoflavone-6,7-di-o-b-D-glucopyranoside	Flavonoids Classification of Application Fields Leguminosae Source classification Other Diseases Phenols Polyphenols Pueraria montana (Loureiro) Merrill Plants Disease Research Fields Isoflavones	Others
5,6,7,40-Tetrahydroxyisoflavone-6,7-di-o-b-D-glucopyranoside is an isoflavonoid glycoside isolated from Pueraria lobata .

HY-N8329

AS-2077715	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal Antibiotic
AS-2077715 is an antifungal agent that shows inhibitory activity against the Trichophyton species. AS-2077715 can be obtained from the fermentation broth of Capnodium sp. 339855. AS-2077715 can be used to study fungal infections .

HY-N0749

Jatrorrhizine	Alkaloids Monophenols other families Source classification Phenols Plants Isoquinoline Alkaloids	Cholinesterase (ChE) 5-HT Receptor Bacterial
Jatrorrhizine is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine is a potent and orally active inhibitor of AChE (IC₅₀=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .

HY-N0740

Jatrorrhizine chloride	Alkaloids Monophenols Source classification Ranunculaceae Coptis chinensis Franch. Phenols Plants Isoquinoline Alkaloids	Cholinesterase (ChE) 5-HT Receptor Bacterial
Jatrorrhizine chloride is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine chloride is a potent and orally active inhibitor of AChE (IC₅₀=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine chloride reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .

HY-N0749A

Jatrorrhizine hydroxide	Alkaloids Monophenols Source classification Ranunculaceae Coptis chinensis Franch. Phenols Plants Isoquinoline Alkaloids	Cholinesterase (ChE) 5-HT Receptor Bacterial
Jatrorrhizine hydroxide is an alkaloid isolated from Coptis chinensis with neuroprotective, antimicrobial, antiplasmodial and antioxidant activities . Jatrorrhizine hydroxide is a potent and orally active inhibitor of AChE (IC₅₀=872 nM) over >115-fold selectivity for BuChE . Jatrorrhizine hydroxide reduces uptake of serotonin (5-HT) and norepinephrine (NE) via inhibition of uptake-2 transporters .

HY-N10922

(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone	Structural Classification Terpenoids Source classification Celastraceae Diterpenoids Celastrus Plants	Others
(3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3), a Palmitate, can be isolated from the root tissue of Salvia miltiorrhiza. (3S,4aS,10aS)-3-(Acetyloxy)-2,3,4,4a,10,10a-hexahydro-6-hydroxy-1,1,4a-trimethyl-7-(1-methylethyl)-9(1H)-phenanthrenone (compound 3) shows anti-cancer activity against human cancer cell lines with DC₅₀s of 25.5 μg/mL (HeLa), 37.5 μg/mL (HepG2), 30.2 μg/mL (OVCAR-3), respectively .

HY-N10536

Halichondrin B	Structural Classification Natural Products Classification of Application Fields Animals Marine natural products Sponge Disease Research Fields Cancer	Others
Halichondrin B is found from the sponge Halichondria okadai. Halichondrin B is a noncompetitive inhibitor of Vinca-alkaloid binding to tubulin (IC₅₀ for tubulin polymerization of 1.2-1.4 μM). Halichondrin B shows anti-tumor activity .

HY-N10906

(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Lauraceae Lindera aggregata (Sims) Kosterm.	Others
(4R,4aS,5aS,6aR,6bS,7aR)-4-Hydroxy-3,6b-dimethyl-5-methylene-4,4a,5,5a,6,6a,7,7a-octahydrocyclopropa[2,3]indeno[5,6-b]furan-2(6bH)-one is a sesquiterpene lactone .

HY-N11163

(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate	Structural Classification Terpenoids Source classification Diterpenoids Plants Compositae Solidago virgaurea L.	Others
(Z)-(1R,3R,4R,4aS,8R,8aR)-3,4,8,8a-Tetramethyl-7-oxo-4-(2-(5-oxo-2,5-dihydrofuran-3-yl)ethyl)decahydronaphthalen-1-yl 2-methylbut-2-enoate (compound 7a) is a clerodane diterpene .

HY-N0926A

Columbamine chloride Columbamin chloride; Dehydroisocorypalmine chloride	Structural Classification Alkaloids Mahonia bealei (Fort.) Carr. Source classification Quinoline Alkaloids Plants Berberidaceae	Others
Columbamine (Columbamin; Dehydroisocorypalmine) chloride is an alkaloid .

Species:	Human (19) Virus (1)
Tag:	His (17) SUMO (1) Strep (1) Tag Free (1) Avi (1) GST (6) Flag (4)
Source:	HEK293 (4) Sf9 insect cells (7) E. coli (9)

Cat. No.	Compare	Product Name	Species	Source

HY-P702671

	CDK1-CCNA2 Protein, Human (sf9, GST, His) CDK1; cyclin-dependent kinASe 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinASe; cell cycle controller CDC2; cell division protein kinASe 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells

HY-P702673

	CDK1-CCNE1 Protein, Human (sf9, GST, His, Flag) CDK1; cyclin-dependent kinASe 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinASe; cell cycle controller CDC2; cell division protein kinASe 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells

HY-P702674

	CDK1-CCNE2 Protein, Human (sf9, GST, His, Flag) CDK1; cyclin-dependent kinASe 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinASe; cell cycle controller CDC2; cell division protein kinASe 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells

HY-P702736

	CDK1-CCNB1 Protein, Human (sf9, GST, Flag, His) CDK1; cyclin-dependent kinASe 1; CDC2, cell division cycle 2, G1 to S and G2 to M; CDC28A; p34 protein kinASe; cell cycle controller CDC2; cell division protein kinASe 1; cell division control protein 2 homolog; cell division cycle 2, G1 to S and G2 to M; CDC2; P34CDC2; MGC111195; DKFZp686L20222	Human	Sf9 insect cells

HY-P7794

	CD158d/KIR2DL4 Protein, Human (HEK293, His) rHuCD158d, His; Killer Cell Immunoglobulin-Like Receptor 2DL4; CD158 Antigen-Like Family Member D; KIR-103AS; MHC ClASs I NK Cell Receptor KIR103AS; CD158d; KIR2DL4; KIR103AS	Human	HEK293
	CD158d/KIR2DL4 Protein, Human (HEK293, His) is a recombinant human CD158d expressed in HEK 293 cells with a His tag at the N-terminus. CD158d/KIR2DL4 Protein is an NK cell-activating receptor with inhibitory potential.

HY-P71134

	WARS Protein, Human (His) WARS also known AS Tryptophanyl-tRNA synthetASe; Interferon-induced protein 53.	Human	E. coli
	WARS includes isomer 1, isomer 2, T1-TrpRS and T2-TrpRS, and has aminoacylation activity, except T2-TrpRS. Unlike isoform 1, isoform 2, T1-TrpRS and T2-TrpRS, exhibit vasostatic activity. WARS Protein, Human (His) is the recombinant human-derived WARS protein, expressed by E. coli , with N-6*His labeled tag. The total length of WARS Protein, Human (His) is 471 a.a., with molecular weight of ~60.0 kDa.

HY-P7868

	Cystatin A/CSTA Protein, Human (His) rHuCystatin-A, His; Cystatin-A; Cystatin-AS; Stefin-A; CSTA; STF1; STFA	Human	E. coli
	Cystatin A (CSTA) protein is an intracellular thiol protease inhibitor critical for desmosome-mediated intercellular adhesion, especially in the epidermis. Its role as a protease inhibitor is essential for regulating cellular proteolytic activity. Cystatin A/CSTA Protein, Human (His) is the recombinant human-derived Cystatin A/CSTA protein, expressed by E. coli , with N-6*His labeled tag. The total length of Cystatin A/CSTA Protein, Human (His) is 97 a.a., with molecular weight of ~14.0 kDa.

HY-P75886

	Nucleocapsid/NP Protein, H7N9 (R4NE06, sf9, His) Influenza A H7N9 (A/Shanghai/2/2013) Nucleocapsid / NP Protein (His)	Virus	Sf9 insect cells
	Nucleoprotein/NP is critical in the influenza virus life cycle, encapsulating the negative-strand viral RNA to form a ribonucleoprotein (RNP) template. The nuclear localization signal of NP guides RNP into the host cell nucleus through α/β import. Nucleocapsid/NP Protein, H7N9 (R4NE06, sf9, His) is the recombinant Virus-derived Nucleocapsid/NP protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of Nucleocapsid/NP Protein, H7N9 (R4NE06, sf9, His) is 498 a.a., with molecular weight of ~57 kDa.

HY-P701530

	ANKFY1 Protein, Human (Sf9, His, Strep) ANKFY1; Rabankyrin-5; Rank-5; Ankyrin repeat and FYVE domain-containing protein 1; Ankyrin repeats hooked to a zinc finger motif	Human	Sf9 insect cells
	ANKFY1 is a proposed Rab5 effector that critically participates in endosomal dynamics by binding to PI(3)P, promoting homotypic early endosomal fusion and participating in heterotypic fusion. It plays a crucial role in macropinocytosis, is dependent on Rab5-GTP, and is essential for the correct localization of activated tyrosine kinase receptors such as PDGFRB. ANKFY1 Protein, Human (Sf9, His, Strep) is the recombinant human-derived ANKFY1 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of ANKFY1 Protein, Human (Sf9, His, Strep) is 1168 a.a., .

HY-P70252

	LCAT Protein, Human (HEK293, His) rHuPhosphatidylcholine-sterol acyltransferASe/LCAT, His; Phosphatidylcholine-sterol acyltransferASe; also named Lecithin-cholesterol acyltransferASe; Phospholipid-cholesterol acyltransferASe and LACT; is an extracellular cholesterol esterifying enzyme which belongs to the AB hydrolASe superfamily	Human	HEK293
	LCAT protein is synthesized in the liver and plays a vital role in the metabolism of plasma lipoproteins by converting cholesterol and phosphatidylcholine in HDL and LDL. LCAT Protein, Human (HEK293, His) is the recombinant human-derived LCAT protein, expressed by HEK293 , with C-6*His labeled tag. The total length of LCAT Protein, Human (HEK293, His) is 416 a.a., with molecular weight of ~71 kDa.

HY-P71682

	YWHAH Protein, Human (GST) 14-3-3 protein eta; Brain protein 14-3-3; eta isoform; HGNC:12853; Protein AS1; YWHA 1; YWHA1; Ywhah	Human	E. coli
	YWHAH protein, an adapter in diverse signaling pathways, recognizes phosphoserine or phosphothreonine motifs, modulating partner activity upon binding. It negatively regulates PDPK1 kinase activity and interacts with nuclear hormone receptors (AR, ESR1, ESR2, MC2R, NR3C1, NRIP1, PPARBP, THRA) and cofactors. Additionally, it interacts with phosphorylated ABL1, retaining it in the cytoplasm, and weakly with CDKN1B. Interactions involve ARHGEF28, CDK16, GAB2, KCNK18 (phosphorylation-dependent), SAMSN1, phosphorylated PDPK1, phosphorylated DAPK2, PI4KB, TBC1D22A, TBC1D22B, SLITRK1, and MEFV, highlighting its multifunctional role. YWHAH Protein, Human (GST) is the recombinant human-derived YWHAH protein, expressed by E. coli, with N-GST labeled tag. The total length of YWHAH Protein, Human (GST) is 243 a.a., with molecular weight of ~54.9 kDa.

HY-P701552

	RNF135 Protein, Human RNF135; E3 ubiquitin-protein ligASe RNF135; RIG-I E3 ubiquitin ligASe; REUL; RING finger protein 135; RING finger protein leading to RIG-I activation; Riplet; RING-type E3 ubiquitin transferASe RNF135	Human	E. coli
	The RNF135 protein acts as an E2-dependent E3 ubiquitin protein ligase and serves as a RIGI coreceptor for viral RNA sensing and activation of antiviral innate immune responses. RNF135 Protein, Human is the recombinant human-derived RNF135 protein, expressed by E. coli , with tag free. The total length of RNF135 Protein, Human is 431 a.a., .

HY-P701553

	RNF135 Protein, Human (His) RNF135; E3 ubiquitin-protein ligASe RNF135; RIG-I E3 ubiquitin ligASe; REUL; RING finger protein 135; RING finger protein leading to RIG-I activation; Riplet; RING-type E3 ubiquitin transferASe RNF135	Human	E. coli
	The RNF135 protein acts as an E2-dependent E3 ubiquitin protein ligase and serves as a RIGI coreceptor for viral RNA sensing and activation of antiviral innate immune responses. RNF135 Protein, Human (His) is the recombinant human-derived RNF135 protein, expressed by E. coli , with N-6*His labeled tag. The total length of RNF135 Protein, Human (His) is 431 a.a., .

HY-P72179

	ELANE Protein, Human (GST) Bone marrow serine proteASe; ELA2; ELAne; ElAStASe 2; ElAStASe 2 neutrophil; ElAStASe neutrophil expressed; ElAStASe-2; ELne_HUMAN; GE; Granulocyte derived elAStASe; HLE; Hne; Human leukocyte elAStASe; Leukocyte elAStASe; MedullASin; ne; neutrophil elAStASe; PMN E; PMN elAStASe; Polymorphonuclear elAStASe; SCN1	Human	E. coli
	ELANE is a serine protease that critically regulates natural killer cells, monocytes, and granulocytes by inhibiting C5a-dependent neutrophil enzyme release and chemotaxis, thereby shaping immune responses. It also inhibits pyroptosis by cleaving GSDMB, affecting the regulation of programmed cell death. ELANE Protein, Human (GST) is the recombinant human-derived ELANE protein, expressed by E. coli , with N-GST labeled tag. The total length of ELANE Protein, Human (GST) is 238 a.a., with molecular weight of ~52.6 kDa.

HY-P72204

	Growth Hormone R/GHR Protein, Human (His-SUMO) GH receptor; GH-binding protein; GHBP; GHBP, included; GHR; GHR_HUMAN; Growth hormone binding protein; Growth hormone receptor; Growth hormone receptor precursor; Growth hormone-binding protein; Growth hormone-binding protein, included; IncreASed responsiveness to growth hormone, included; Serum binding protein; Serum-binding protein; Somatotropin receptor	Human	E. coli
	Growth Hormone R (GHR) is the receptor for pituitary growth hormone, crucial in postnatal body growth regulation. Binding to its ligand activates the JAK2/STAT5 pathway, facilitating intracellular signaling. The soluble form, GHBP (Growth Hormone Binding Protein), acts as a growth hormone reservoir in the bloodstream. GHBP may modulate or inhibit growth hormone signaling, contributing to intricate growth process regulation. Growth Hormone R/GHR Protein, Human (His-SUMO) is the recombinant human-derived Growth Hormone R/GHR protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag. The total length of Growth Hormone R/GHR Protein, Human (His-SUMO) is 246 a.a., with molecular weight of ~44.4 kDa.

HY-P702727

	FYN Protein, Human (Biotinylated, sf9, His, Flag, Avi) FYN; FYN oncogene related to SRC, FGR, YES; tyrosine-protein kinASe Fyn; MGC45350; SLK; SYN; src-like kinASe; proto-oncogene Syn; c-syn protooncogene; proto-oncogene c-Fyn; src/yes-related novel; tyrosine kinASe p59fyn(T); OKT3-induced calcium influx regulator; p59-FYN	Human	Sf9 insect cells

HY-P71369

	TINAGL1 Protein, Human (HEK293, His) Tubulointerstitial nephritis antigen-like (TINAGL1); also known AS Glucocorticoid-inducible protein 5; Oxidized LDL-responsive gene 2 protein; TIN Ag-related protein; Tubulointerstitial nephritis antigen-related protein; GIS5; LCN7; OLRG2 and TINAGL	Human	HEK293
	TINAGL1 Protein, implicated in adrenocortical zonation, may regulate distinct adrenal cortex zones and repress CYP11B1 gene expression in adrenocortical cells. As a member of the non-catalytic peptidase C1 family, its distinctive function does not involve enzymatic activity. Unraveling TINAGL1's molecular pathways could offer insights into its role in adrenal physiology, shedding light on its potential to manipulate adrenal function. TINAGL1 Protein, Human (HEK293, His) is the recombinant human-derived TINAGL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TINAGL1 Protein, Human (HEK293, His) is 446 a.a., with molecular weight of 55-60 kDa.

HY-P70220

	MPZL1 Protein, Human (HEK293, His) rHuMyelin protein zero-like protein 1/MPZL1, His; Myelin protein zero-like 1; isoform CRA_b; cDNA FLJ78597; highly similar to Homo sapiens myelin protein zero-like 1 (MPZL1); transcript variant 1; mRNA ; cDNA; FLJ96614; Homo sapiens myelin protein zero-like 1 (MPZL1); Mrna	Human	HEK293
	MPZL1 protein is a cell surface receptor that participates in signal transduction by recruiting PTPN11/SHP-2 to the cell membrane. MPZL1 Protein, Human (HEK293, His) is the recombinant human-derived MPZL1 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of MPZL1 Protein, Human (HEK293, His) is 127 a.a., with molecular weight of 20-28 kDa.

HY-P702747

	PAK4 Protein, Human (His) PAK4; p21 protein (Cdc42/Rac)-activated kinASe 4; p21(CDKN1A) activated kinASe 4; serine/threonine-protein kinASe PAK 4; PAK-4; p21-activated kinASe 4; p21(CDKN1A)-activated kinASe 4; protein kinASe related to S. cerevisiae STE20, effector for Cdc42Hs	Human	E. coli

HY-P702744

	STK4 Protein, Human (His) STK4; serine/threonine kinASe 4; serine/threonine-protein kinASe 4; kinASe responsive to stress 2; KRS2; mammalian sterile 20 like 1; MST1; yeASt Ste20 like; YSK3; MST-1; STE20-like kinASe MST1; mammalian sterile 20-like 1; mammalian STE20-like protein kinASe 1; serine/threonine-protein kinASe Krs-2; dJ211D12.2 (serine/threonine kinASe 4 (MST1, KRS2)); DKFZp686A2068	Human	E. coli

Cat. No.	Product Name	Chemical Structure

HY-W008794S

Normetanephrine-d3 hydrochloride
Normetanephrine-d₃ (hydrochloride) is the deuterium labeled Normetanephrine hydrochloride. Normetanephrine ((±)-Normetanephrine) hydrochloride is the O-methylated metabolite of norepinephrine (NE)[1].

HY-B0196S

Venlafaxine-d6
Venlafaxine-d₆ is the deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

HY-18600AS

Azimilide-d8 dihydrochloride
Azimilide-d₈ (dihydrochloride) is the deuterium labeled Azimilide dihydrochloride. Azimilide Dihydrochloride (NE-10064 Dihydrochloride) is a class III antiarrhythmic compound, inhibits I(Ks) and I(Kr) in guinea-pig cardiac myocytes and I(Ks) (minK) channels expressed in Xenopus oocytes.

HY-144246S

Zofenoprilat-NES-d5

Zofenoprilat-NES-d₅ is the deuterium labeled Zofenoprilat-NES[1].

HY-124414S

4'-Hydroxytamoxifen-d6 (contains up to 10% E isomer)
4'-Hydroxytamoxifen-d₆ (contains up to 10% E isomer) is deuterium labeled 4'-Hydroxy Tamoxifen. 4'-Hydroxytamoxifen is a metabolite of Tamoxifen.

HY-B0196AS1

Venlafaxine-d6 hydrochloride
Venlafaxine-d₆ (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine hydrochloride (Wy 45030 hydrochloride) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

HY-B0196AS

Venlafaxine-d10 hydrochloride
Venlafaxine-d₁₀ (hydrochloride) is the deuterium labeled Venlafaxine hydrochloride. Venlafaxine (Wy 45030) hydrochloride is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1][2].

HY-B0196S1

Venlafaxine-d6-1
Venlafaxine-d₆-1 is deuterium labeled Venlafaxine. Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].

HY-A0130S

Sulfalene-13C6

Sulfalene- ¹³C₆ is the ¹³C₆ labeled Sulfalene. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial .

HY-N7404S

Nε,Nε,Nε-Trimethyllysine-d9 chloride
Nε,Nε,Nε-Trimethyllysine-d₉ (chloride) is the deuterium labeled Nε,Nε,Nε-Trimethyllysine (chloride)[1]. Nε,Nε,Nε-Trimethyllysine chloride serves as a precursor for gut flora-dependent formation of N,N,N-trimethyl-5-aminovaleric acid (TMAVA)[2].

HY-A0052S

(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d4
(1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide-d₄ is deuterated labeled (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1R)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide.

Cat. No.	Product Name	Application	Reactivity

HY-P82425

AS160 Antibody (YA2170)

AS160; NIDDM5
WB, IP Human
HY-P83652

Goat Anti-Mouse/Rabbit lgG(H&L)-HRP (Ready to use)

IHC Human
HY-P83015

Cystatin A Antibody (YA2760)

CSTA; STF1; STFA; Cystatin-A; Cystatin-AS; Stefin-A
WB, FC Human, Mouse, Rat
HY-P83635

RES Antibody (YA3380)

NRSF; RE1 silencing transcription factor; Repressor binding to the X2 box; rest; X2 box repressor; XBR
WB Human

HY-P80828

Phospho-IRE1 (Ser724) Antibody ERN1; IRE1; Serine/threonine-protein kinASe/endoribonucleASe IRE1; EndoplASmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a	WB, IP	Human
Phospho-IRE1 (Ser724) Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 110 kDa, targeting to Phospho-IRE1 (Ser724). It can be used for WB,IP assays with tag free, in the background of Human.

HY-P83440

Polycomb Protein SUZ12 Antibody (YA3185) SUZ12; CHET9; JJAZ1; KIAA0160; Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog	WB, ICC/IF, IP	Human, Mouse, Rat

HY-P80525

14-3-3 eta Antibody (YA838) 14-3-3 protein eta; 1433F_HUMAN; Brain protein 14-3-3; eta isoform; HGNC:12853; Protein AS1; Tyrosine 3/tryptophan 5 monooxygenASe activation protein eta polypeptide; YWHA 1; YWHA1; Ywhah.	WB	Human, Mouse, Rat
14-3-3 eta Antibody (YA838) is a non-conjugated and Mouse origined monoclonal antibody about 28 kDa, targeting to 14-3-3 eta (5F2). It can be used for WB assays with tag free, in the background of Human, Mouse, Rat.

HY-P80785

PGP9.5 Antibody UCHL1 / PGP9.5; UCHL1; B220; CD 45; CD45; cd45 antigen; ec3.1.3.48; GP 180; GP180; Human homolog of severe combined immunodeficiency due to PTPRC deficiency; L CA; L-CA; lca; Leukocyte common antigen; LY 5; LY5; Protein tyrosine phosphatASe receptor type	WB, IHC-F, IHC-P, ICC/IF, IP	Human, Mouse, Rat
PGP9.5 Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 25 kDa, targeting to PGP9.5. It can be used for WB,IHC-F,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat.

HY-P81215

Neutrophil Elastase Antibody Bone Marrow Serine ProteASe; ELA 2; ELA2; ELAne; ElAStASe 2; ElAStASe-2; ElAStASe 2 neutrophil; ElAStASe neutrophil expressed; ElAStASe-2; ELne_HUMAN; GE antibody Granulocyte derived elAStASe; HLE; Hne; Human leukocyte elAStASe; Leukocyte elAStASe; Leukocyte ElAStASe Precursor; MedullASin; ne; neutrophil elAStASe; neutrophill elAStASe; PMN E; PMN ElAStASe; Polymorphonuclear elAStASe; SCN1; Serine proteASe; SERP1.	WB; ELISA; Flow-Cyt;	Human, Mouse, Rat(predicted: Dog)
Neutrophil Elastase Antibody is an unconjugated, approximately 26 kDa, rabbit-derived, anti-Neutrophil Elastase polyclonal antibody. Neutrophil Elastase Antibody can be used for: WB, ELISA, Flow-Cyt, expriments in human, mouse, rat, and predicted: dog background without labeling.

HY-P81171

MCP1 Antibody MCP-1/CCL2; C-C motif chemokine 2; CCL 2; CCL2; CCL2_HUMAN; Chemokine (C C motif) ligand 2; Chemokine C C motif ligand 2; Chemokine CC Motif Ligand 2; GDCF 2; GDCF 2 HC11; GDCF-2; GDCF2; HC11; HSMCR30; HSMCR30; JE; MCAF; MCP 1; MCP-1; MGC9434; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; Monocyte chemotactic protein 1; Monocyte secretory protein JE; SCYA2; Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig je); Small inducible cytokine A2; Small inducible cytokine subfamily A (Cys Cys), member 2; Small inducible cytokine subfamily A Cys Cys member 2; Small-inducible cytokine A2; SMC CF; SMC-CF; SMCCF.	WB; ELISA; IHC-P; IHC-F; Flow-Cyt; IF	Human, Rat(predicted: Mouse, Dog, Pig, Horse, Rabbit)
MCP1 Antibody is an unconjugated, approximately 11 kDa, rabbit-derived, anti-MCP1 polyclonal antibody. MCP1 Antibody can be used for: WB, ELISA, IHC-P, IHC-F, Flow-Cyt, IF expriments in human, rat, and predicted: mouse, dog, pig, horse, rabbit background without labeling.

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